Synonymous codon usage and variations in the level of isoaccepting tRNAs exert a powerful selective force on translation fidelity.We have developed an algorithm to evaluate the relative rate of translation which allows large-scale comparisons of the non-uniform translation rate on the protein biogenesis.Using the complete genomes of Escherichia col
The novel antimicrotubular taxane called cabazitaxel was developed to avoid the Bike Units - Comfort - Step-Thru primary mechanism of resistance for docetaxel, the first-line treatment for patients with hormone-resistant prostate cancer (HRPC).However, its ability to increase the survival rate for HRPC is limited to a few months, and cabazitaxel-re
Tachycardia-induced cardiomyopathy (TIC) is characterized by reversible left ventricular (LV) dysfunction caused by long-standing tachycardia.The diagnosis of TIC is challenging due to lack of guidelines and specific OIl assessment tools.Advanced imaging and endomyocardial biopsy should be taken into consideration in the future as contributors in t
Rouder and Haaf (2021, this issue) propose a focus shift toward qualitative individual differences in cognition and present a research toolkit for doing so.In this invited commentary, I will argue that the observation of qualitative Racks individual differences may be no more than an indicator that more theoretical and empirical work needs to be do